Discover ongoing clinical trials that may further our pipeline.

Study Locations

Ongoing Motixafortide Clinical Trials

Investigator-initiated studies of motixafortide are currently enrolling patients in the following locations:

sickle cell pin
Sickle Cell Disease
pancreatic cancer pin
Pancreatic Cancer
A map of Northeast USA with pins indicating BioLine clinical trial sites for sickle cell disease and pancreatic cancer.
STUDY TITLE

A Pilot Safety and Feasibility Study to Evaluate Motixafortide (CXCR4/SDF-1 Inhibition) and Natalizumab (VLA-4/VCAM-1 Inhibition) as a Novel Regimen to Mobilize CD34+ Hematopoietic Stem Cells for Gene Therapies in Sickle Cell Disease (SCD)

CLINICAL PARTNER
Washington University in St. Louis logo
CONDITION

Sickle Cell Disease

STUDY LOCATION
St. Louis, MO
PHASE
Phase 1
INFORMATION
STUDY TITLE

Sickle Cell Disease Stem Cell Mobilization and Apheresis Using Motixafortide

CLINICAL PARTNER
Washington University in St. Louis logo
CONDITION

Sickle Cell Disease

STUDY LOCATION
Memphis, TN
PHASE
Phase 1
INFORMATION
STUDY TITLE

A Phase 2b Study with Combination Chemotherapy (Gemcitabine and Nab-Paclitaxel), Chemokine (C-X-C) Motif Receptor 4 Inhibitor (BL-8040), and Immune Checkpoint Blockade (Cemiplimab) in Metastatic Treatment-naïve Pancreas Adenocarcinoma

CLINICAL PARTNER
Washington University in St. Louis logo
CONDITION

Pancreatic Cancer

STUDY LOCATION
New York, NY
Providence, RI
PHASE
Phase 2b
INFORMATION

For more information on BioLineRx’s clinical trials, please contact MedInfo@biolinerx.com.

Research Areas of Focus for Motixafortide

BioLineRx’s commitment to patients in need is supported not only through our own clinical studies, but also by supporting independent, unsolicited research relating to motixafortide by external investigators, organizations, and institutions as part of our Investigator Initiated Studies (IIS) program. IIS proposals submitted to BioLineRx are reviewed by our scientific and medical committees for scientific merit as well as safety, legal, ethical, and budgetary considerations. Support by BioLineRx can take the form of funding, study drug, or a combination of both.

  • Stem cell mobilization
  • CXCR4 inhibition in immuno-oncology
  • Exploration of the role of motixafortide in reducing rates of myelosuppression
  • Pharmacoeconomic studies
  • Quality of life studies

To submit a proposal or for any further information, please email IIS@biolinerx.com.

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White Curve shaped
Drugs on the way to the finish line

Learn about our growing pipeline of best-in-class therapeutics for patients with cancer and rare disease.